Category Archives: LIVESTOCK-FISH

AHH / CCPP / Disease Control / ILRI / LIVESTOCK-FISH / LIVESTOCKCRP / Vaccines

Development of a challenge model for contagious caprine pleuropneumonia (CCPP)

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Flavio Sacchinia,b, Anne Liljandera, Elise Schiecka and Joerg Joresa,c aInternational Livestock Research Institute, Box 30709, 00100, Nairobi, Kenya bIstitututo Zooprofilattico Sperimentale dell’Abruzzo e del Molise, via campo Boario 64100, Teramo. Italy. cInstitute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Länggass-Str. 122, Postfach 3001, Bern, Switzerland Contagious caprine pleuropneumonia (CCPP) is a severe respiratory disease affecting … Continue reading →

Africa / AHH / Cattle / CBPP / ILRI / LIVESTOCK-FISH / LIVESTOCKCRP / Vaccines

Towards improved vaccines against contagious bovine pleuropneumonia (CBPP)

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Elise Schiecka, Anne Liljandera and Joerg Joresa,b aInternational Livestock Research Institute, Box 30709, 00100, Nairobi, Kenya bInstitute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Länggass-Str. 122, Postfach 3001, Bern, Switzerland Contagious bovine pleuropneumonia (CBPP), caused by Mycoplasma mycoides subsp. mycoides (Mmm), remains one of the most important infectious diseases of cattle in sub-Saharan Africa. CBPP … Continue reading →

Africa / AHH / Animal Diseases / ASF / China / Disease Control / LIVESTOCK-FISH / LIVESTOCKCRP / Swine / Vaccines

Establishment of a vaccine technology platform for African swine fever as the first target

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Lucilla Steinaa1, Walter Fuchs2, Hussein Abkallo1, Nicholas Svitek1, Vish Nene1, Anna Lacasta1, Nacyra Assa-Garcia3, Sanjay Vashee3 1International Livestock Research Institute (ILRI), 2Friedrich Loeffler Institute (FLI), 3J. Craig Venter Institute (JCVI). ILRI is working together with JCVI and FLI on an exciting project for the development of a platform for rapid production of attenuated African swine … Continue reading →

AHH / Animal Diseases / Cattle / Disease Control / East Africa / ECF / ILRI / LIVESTOCK-FISH / LIVESTOCKCRP / Vaccines

Progress in developing next generation vaccines for the control of East Coast fever.

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Anna Lacasta1, James Nyagwange1, Nicholas Svitek1, Samuel Oyola1, Sonal Henson1, Lucilla Steinaa1, Vish Nene1, Ine de Goeyse2, Neena Mitter3, Michael Yu3, Fred Fellouse4, Neil King5 1International Livestock Research Institute (ILRI), 2Institute for Tropical Medicine, 3Univeristy of Queensland, 4Univeristy of Toronto, 5University of Washington. East Coast fever is present in 11 countries where roughly 28 million … Continue reading →

AHH / Animal Diseases / Cattle / Disease Control / East Africa / LIVESTOCK-FISH / LIVESTOCKCRP / Pastoralism / Vaccines

Malignant catarrhal fever – a wildebeest associated killer disease of cattle

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Ironically, the 8th Wonder of the World, the annual wildebeest migration in east Africa, causes a recurring hardship to livestock farmers as wildebeest calving is associated with seasonal malignant catarrhal fever (MCF) outbreaks in cattle, that is often fatal. This has led to a traditional disease avoidance strategy by Maasai and other cattle owners, where … Continue reading →

Africa / AHH / Cattle / CBPP / Disease Control / East Africa / ILRI / Impact Assessment / Kenya / LIVESTOCK-FISH / LIVESTOCKCRP / Pastoralism / Vaccines

Micro-economic analysis of the potential impact of contagious bovine pleuropneumonia and its control by vaccination in Narok district of Kenya

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There is inadequate herd and community level information on the impact of CBPP and its control by vaccination to allow adequate allocation of resources for CBPP control in affected ecosystems of Kenya. A study was designed in Narok district to provide this crucial information for the Maasai ecosystem. Continue reading →

AHH / Cattle / Disease Control / ECF / ILRI / LIVESTOCK-FISH / LIVESTOCKCRP / Vaccines

Approaches to vaccination against Theileria parva and Theileria annulata

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There is a great deal of similarity in the immunopathology, genomics and biology of T. parva and T. annulata. Similar protective immune responses are directed against the sporozoite and schizont stages of the parasites, and it is remarkable that many candidate sporozoite and schizont antigens are also so similar to each other. Hence, advances in development of subunit vaccines against one parasite species are likely to be readily applicable to the other. Continue reading →

Africa / AHH / Animal Diseases / Cattle / East Africa / ECF / ILRI / LIVESTOCK-FISH / Vaccines

How to validate an antigen candidate for T. parva

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The ECF consortium is aiming at producing a vaccine that would trigger both an antibody response and a T cell dependent response. Thanks to the whole genome sequence of Theileria parva and its annotation, we have short listed hundreds of antigen candidates, but the number of antigen candidate that can be tested in cattle is limited. How do we narrow down the list of candidates to a handful that can be studied rigorously in live experiments? Continue reading →

Africa / AHH / Animal Diseases / Cattle / East Africa / ECF / ILRI / LIVESTOCK-FISH / Uncategorized / Vaccines

Can we remix the East Coast fever Muguga cocktail?

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The recent meeting of the East Coast fever consortium, which brings together experts in immunology, parasitology and genomics from three continents (ILRI, Edinburgh, Antwerp, IGS, as well as the organization that produces the infection and treatment method (ITM) vaccine, provided a venue to discuss a way forward. Continue reading →