Scientists at the International Livestock Research Institute (ILRI) Animal and Human Health program and a newly established platform that aims to transform animal health services and solutions in low-and middle-income countries (TAHSSL) have developed a panel of new procedures for measuring the immunological activity of livestock blood samples to a specific pathogen. Known as antibody assays, it uses antigen-specific blood serum from animals … Continue reading
Category Archives: Animal Diseases
Development of a challenge model for contagious caprine pleuropneumonia (CCPP)
Flavio Sacchinia,b, Anne Liljandera, Elise Schiecka and Joerg Joresa,c aInternational Livestock Research Institute, Box 30709, 00100, Nairobi, Kenya bIstitututo Zooprofilattico Sperimentale dell’Abruzzo e del Molise, via campo Boario 64100, Teramo. Italy. cInstitute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Länggass-Str. 122, Postfach 3001, Bern, Switzerland Contagious caprine pleuropneumonia (CCPP) is a severe respiratory disease affecting … Continue reading
Towards improved vaccines against contagious bovine pleuropneumonia (CBPP)
Elise Schiecka, Anne Liljandera and Joerg Joresa,b aInternational Livestock Research Institute, Box 30709, 00100, Nairobi, Kenya bInstitute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Länggass-Str. 122, Postfach 3001, Bern, Switzerland Contagious bovine pleuropneumonia (CBPP), caused by Mycoplasma mycoides subsp. mycoides (Mmm), remains one of the most important infectious diseases of cattle in sub-Saharan Africa. CBPP … Continue reading
Establishment of a vaccine technology platform for African swine fever as the first target
Lucilla Steinaa1, Walter Fuchs2, Hussein Abkallo1, Nicholas Svitek1, Vish Nene1, Anna Lacasta1, Nacyra Assa-Garcia3, Sanjay Vashee3 1International Livestock Research Institute (ILRI), 2Friedrich Loeffler Institute (FLI), 3J. Craig Venter Institute (JCVI). ILRI is working together with JCVI and FLI on an exciting project for the development of a platform for rapid production of attenuated African swine … Continue reading
Progress in developing next generation vaccines for the control of East Coast fever.
Anna Lacasta1, James Nyagwange1, Nicholas Svitek1, Samuel Oyola1, Sonal Henson1, Lucilla Steinaa1, Vish Nene1, Ine de Goeyse2, Neena Mitter3, Michael Yu3, Fred Fellouse4, Neil King5 1International Livestock Research Institute (ILRI), 2Institute for Tropical Medicine, 3Univeristy of Queensland, 4Univeristy of Toronto, 5University of Washington. East Coast fever is present in 11 countries where roughly 28 million … Continue reading
Malignant catarrhal fever – a wildebeest associated killer disease of cattle
Ironically, the 8th Wonder of the World, the annual wildebeest migration in east Africa, causes a recurring hardship to livestock farmers as wildebeest calving is associated with seasonal malignant catarrhal fever (MCF) outbreaks in cattle, that is often fatal. This has led to a traditional disease avoidance strategy by Maasai and other cattle owners, where … Continue reading
Introducing English and Swahili instructional videos on the patterns, signs, symptoms and control of Rift Valley fever
The aim of these short and practical video productions is to improve knowledge of Rift Valley fever and its control measures. To further encourage local communities to participate in surveillance and programs working to better prevent or control the disease, the videos have also been prepared in Swahili. Continue reading
New publication: Immune parameters to p67C antigen adjuvanted with ISA206VG correlate with protection against East Coast fever
Three doses of p67C antigen generated stronger immune responses than two doses. Antibody titres and CD4+ T-cell proliferation correlated with protection against East Coast fever. The number of doses could not be reduced from three to two without compromising the protection. Continue reading
ILRI animal health scientists featured in HealthforAnimals newsletter
The February 2018 issue of the Animal Health Matters newsletter from HealthforAnimals features portraits of four ILRI animal health scientists who are working to develop more effective livestock vaccines. Continue reading
Characterization of the Theileria parva sporozoite proteome
To support research on the biology of T. parva and the identification of additional candidate vaccine antigens, this article reports on the sporozoite proteome as defined by LC–MS/MS analysis. Continue reading