Africa / AHH / Animal Diseases / Cattle / East Africa / ECF / Vaccines

A new component of East Coast Fever disease progression is revealed

It is well established that a primary component of East Coast Fever is parasite-driven proliferation of the cow’s lymphocytes. Unknown until now was the important role of the cow’s macrophages in driving an inflammatory response resulting in injury to blood vessels in the lung and respiratory failure. Continue reading

Africa / Animal Diseases / East Africa / Goats / Kenya / LiveGene / LIVESTOCK-FISH / PPR / Small Ruminants / Vaccines

Minimum fully protective doses of adenovirus-based DIVA vaccine against peste des petits ruminants virus challenge in East African goats

Peste des petits ruminants virus (PPRV) causes an economically important disease of sheep and goats, primarily in developing countries. It is becoming the object of intensive international control efforts. Current vaccines do not allow vaccinated and infected animals to be distinguished (no DIVA capability). Continue reading

Animal Diseases / Cattle / East Africa / ECF / ILRI / LiveGene / LIVESTOCK-FISH / Tick Unit / Vaccines

Production and dose determination of the Infection and Treatment Method (ITM) Muguga cocktail vaccine used to control East Coast fever in cattle

The Infection and Treatment Method (ITM) of vaccination against the apicomplexan parasite Theileria parva has been used since the early 1970s and is still the only commercially available vaccine to combat the fatal bovine disease, East Coast fever (ECF). The disease is tick-transmitted and results in annual economic losses of at least $300 million per year. Continue reading

AHH / Animal Diseases / ILRI / Vaccines

Keystone Symposia meeting: New approaches to vaccines for human and veterinary tropical diseases

To be held 22-26 May 2016 in Cape Town, an important component of this Keystone Symposia meeting will be to stimulate crosstalk between the human and veterinary vaccine communities by highlighting cross-cutting technical advances and new science and knowledge from laboratory and field research. Continue reading

AHH / Animal Diseases / East Africa / FMD / ILRI / Vaccines

Improving quality assurance along the FMD vaccine production and supply chain

The International Livestock Research Institute (ILRI) is part of a collaborative project that will develop and assess the assays on FMD vaccine strains currently being produced in East Africa by the Kenya Veterinary Vaccines Production Institute (KEVEVAPI), with the intention of transferring the technologies for their future application. Continue reading