Three doses of p67C antigen generated stronger immune responses than two doses. Antibody titres and CD4+ T-cell proliferation correlated with protection against East Coast fever. The number of doses could not be reduced from three to two without compromising the protection. Continue reading
Category Archives: Tick Unit
ILRI animal health scientists featured in HealthforAnimals newsletter
The February 2018 issue of the Animal Health Matters newsletter from HealthforAnimals features portraits of four ILRI animal health scientists who are working to develop more effective livestock vaccines. Continue reading
The biology of Theileria parva and control of East Coast fever—Current status and future trends
Tremendous progress has been made over the last ten years on East Coast fever (ECF) research. Continue reading
Production and dose determination of the Infection and Treatment Method (ITM) Muguga cocktail vaccine used to control East Coast fever in cattle
The Infection and Treatment Method (ITM) of vaccination against the apicomplexan parasite Theileria parva has been used since the early 1970s and is still the only commercially available vaccine to combat the fatal bovine disease, East Coast fever (ECF). The disease is tick-transmitted and results in annual economic losses of at least $300 million per year. Continue reading
A short history of the ‘live’ vaccine protecting Africa’s cattle against East Coast fever
This article provides a short history of the ‘live’ vaccine (officially known as the infection-and-immunization method of immunization) protecting Africa’s cattle against the lethal cattle disease East Coast fever and names the major funding agencies critical to its development over the last four decades and its deployment in more recent years. Continue reading
ILRI to hold special session on tick research at upcoming TTP and STVM conference in South Africa
ILRI is a sponsor of the 12th Biennial Conference of the Society for Tropical Veterinary Medicine (STVM) and the VIII International Conference on Ticks and Tick-borne Pathogens (TTP8) to be held from 24 to 29 August 2014 in Cape Town, South Africa. ILRI will be hosting a special session on tick research on the morning of 24 August. After a temporary absence from the tick research field, ILRI is actively exploring opportunities to re-enter this research arena. Continue reading