Tremendous progress has been made over the last ten years on East Coast fever (ECF) research.
Peste des petits ruminants virus (PPRV) causes an economically important disease of sheep and goats, primarily in developing countries. It is becoming the object of intensive international control efforts. Current vaccines do not allow vaccinated and infected animals to be distinguished (no DIVA capability).
The Infection and Treatment Method (ITM) of vaccination against the apicomplexan parasite Theileria parva has been used since the early 1970s and is still the only commercially available vaccine to combat the fatal bovine disease, East Coast fever (ECF). The disease is tick-transmitted and results in annual economic losses of at least $300 million per year.
LRI and GALVmed recently convened a workshop on the ‘distribution, delivery and improvement of the Infection and Treatment Method vaccine for East Coast fever (ECF)’.
Originally posted on ILRI Clippings:
ILRI-Wellcome projects have investigated the disease pathogens circulating in both people and animals in the communities outside the border town of Busia, Kenya, where smallholders mix crop growing with livestock raising (photo credit: ILRI/Pye-Smith). Voice of America’s Joe DeCapua interview Phil Toye, a scientist with the International Livestock Research Institute…
This article provides a short history of the ‘live’ vaccine (officially known as the infection-and-immunization method of immunization) protecting Africa’s cattle against the lethal cattle disease East Coast fever and names the major funding agencies critical to its development over the last four decades and its deployment in more recent years.